Annealing multicomponent supramolecular gels

How should multicomponent supramolecular gels be characterised?

Low molecular weight gels, or supramolecular gels, are formed when small molecules self-assemble into fibrous structures. Above a critical concentration, the entanglement and cross-linking of these structures leads to the formation of a self-supporting gel. There are many examples where a single component is used to form such gels. There is however an ever-increasing interest in using multiple ...

Nonlinear Effects in Multicomponent Supramolecular Hydrogels.

Multicomponent low molecular weight gels are useful for a range of applications. However, when mixing two components, both of which can independently form a gel, there are many potential scenarios. There is a limited understanding as to how to control and direct the assembly. Here, we focus on a pH-triggered two-component system. At high pH, colloidal structures are formed, and there is a degre...

Functional Polymer Gels by Click- and Supramolecular Chemistry

Local delivery of doxorubicin through supramolecular peptide amphiphile nanofiber gels.

Peptide amphiphiles (PAs) self-assemble into supramolecular nanofiber gels that provide a suitable environment for encapsulation of both hydrophobic and hydrophilic molecules. The PA gels have significant advantages for controlled delivery applications due to their high capacity to retain water, biocompatibility, and biodegradability. In this study, we demonstrate injectable supramolecular PA n...

Supramolecular gels based on boronate esters and imidazolyl donors.

Dative boron-nitrogen bonds can be used for the controlled assembly of boronate esters and N-donor ligands. So far, most investigations have focused on crystalline assemblies. In contrast, there are very few reports about soft materials based on dative B-N bonds. Here, we describe the formation of gels by aggregation of diboronate esters and ditopic bisimidazolyl donor ligands. Analyses of low ...